Frederick L. Lothrop was a registered pharmacist located at 555 Eddy Street in Providence in 1884. Several years later he had another store in operation at 73 Westminister Street. Besides dealing in the usual patent medicines, he manufactured his own LOTHROP'S COUGH ELIXIR, a FRAGRANT TOOTH POWDER, and his own brand of IMPROVED MANDRAKE PILLS.

About 1899, he had several pharmacies in operation at 116 Broadway, 199 Westminister, and 92 Chestnut Street all in Providence.

For some unknown reason, Lothrop quit operating in Rhode Island in 1900 and moved to Boston. A few years later, Lothrop returned to Providence and opened up another shop. However, he only remained here for about a year before packing up again and once more returning to Boston.